the USA
subscriptions
Prescription
Niagen Injectable
No subscription. You’re only charged if a provider approves.
2,000+ patients served
No visit fee. You’re only charged if a provider approves. One-time purchase. Shipping included. Prescription subject to provider approval.
- Cold shipping included
- 503A compounding pharmacy
- Personalized treatments
Niagen doesn’t need to be complicated.
| Order feature |
signal-rx:
Order as you need
|
Niagen subscription plan
|
|---|---|---|
| Subscription required | No | Yes |
| Automatic billing | No | Yes |
| 500 mg Niagen | $350per order | $349per month |
| Compounding pharmacy | Yes | Yes |
Selected subscription plan; see comparison details.
Comparison details
Patriotic Virtual Telehealth lists $349 per month for 500 mg, supplied as 5 mL at 100 mg/mL, with consultation, supplies and cold-chain shipping included. Its month-to-month plan can be cancelled before the next billing date. Checked September 15, 2026. Selected plan only; prices and terms may change. signal-rx lists $350 per 500 mg order, with no visit fee. One order is not represented as a one-month supply.
If prescribed, you choose whether to order.
Join thousands.
Move forward with confidence.
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Quick, simple, easy
I wanted to get a face cream. I was looking for this type of cream for a while and this website has the best price. I ordered and it was a very easy a quick process. I filled out the questionnaire, received a quick approval, paid for the product and received it within 2 days. Great service. Thank you
Great job. Quick response.
I noticed I put the wrong number in my address after I already sent everything. Thought for sure that was going to be a mess. Sent them a message and they fixed it before it shipped. They even let me know it was corrected so I wasn’t sitting there worrying about it.
No surprises at checkout
I liked that I didn’t have to hunt around for the real price. Everything was shown upfront and what I saw was what I paid.
A Truly Positive and Professional Personal Experience
Based on my personal experience, Signal-Rx provides exceptional service and outstanding products, backed by a team that is remarkably knowledgeable, professional, and polite.
How it works
Three steps.
No ongoing commitment.
Get prequalified in 2 minutes.
Complete your online intake with your health information.
Check out. Pay nothing yet.
Your card is only held, not charged. Then verify your ID and answer a few last health questions.
Approved? It ships.
A licensed provider reviews every request within 24 hours. You’re only charged if approved: 500 mg of Niagen for $350, shipping included. A one-time purchase, never a subscription.
What is Niagen?
Niagen is nicotinamide riboside, a form of vitamin B3 your cells use to make NAD+. Here’s why NAD+ matters.
NAD+ production
Niagen supplies a building block your cells use to produce NAD+.
Cellular energy
NAD+ helps your cells turn nutrients into usable energy.
Cellular repair
NAD+ supports enzymes involved in DNA repair and cell maintenance.
Before you start
Niagen injectable FAQs
What happens after I start?
Complete your online intake and pay the one-time $5 non-refundable provider-review fee. A licensed provider reviews your information. If prescribed, you choose whether to order. Future provider reviews have no additional review fee.
What does the $350 cover?
$350 covers 500 mg of Niagen in a 5 mL vial at 100 mg/mL, with syringes, needles, alcohol wipes and shipping included. There’s no visit fee. You’re only charged if a provider approves.
Is this a subscription?
No subscriptions, automatic billing or automatic refills. You choose when to request another order, subject to provider approval.
What if I’m not approved?
You pay nothing. The hold on your card is released, so there is nothing to refund. A prescription is not guaranteed.
What comes with my order?
Your Niagen is cold shipped with syringes, needles and alcohol wipes. A sharps container is not included.
When will my order arrive?
Your order ships within 1 to 2 business days of approval. Most orders arrive within 2 business days after they ship.
See important safety information
Your prescription label and provider instructions control use.
Before treatment
Tell the provider about medical conditions, allergies, medications, supplements, prior injection reactions, pregnancy, or breastfeeding.
Possible reactions and urgent symptoms
Reactions may include injection-site irritation, redness, tenderness, or discomfort. Rotate areas if directed. Stop use and contact your provider if irritation persists, worsens, or other concerning symptoms occur.
When to seek emergency care
Seek urgent medical care for severe allergic, rapidly worsening, or other emergency symptoms. Portal messaging is not for emergencies.
Storage, sterile handling, and disposal
Do not share or change the prescribed use. Follow the pharmacy label for storage, sterile handling, and the beyond-use date. Dispose of used needles and syringes in an appropriate sharps container. One is not supplied. Keep everything away from children.
Complete compounded-medication disclosure
Niagen Injectable is compounded for an individual patient by prescription. Compounded drugs are not FDA-approved, and FDA does not review them for safety, effectiveness, or quality before marketing. The provider determines whether treatment is appropriate.