the USA
subscriptions
Prescription
GHK-Cu Cream
Skin care doesn’t need to be complicated.
| Order feature | signal-rx:  Order as you need |
 GHK-Cu subscription plans |
|---|---|---|
| Cream price | $1150.5% 30 mL per order | $1990.5% 30 mL per month |
| Subscription required | No | Yes |
| Automatic billing | No | Yes |
| 503A pharmacy | Yes | Yes |
Selected monthly plans. See Comparison details.
Comparison details
The other column shows selected monthly GHK-Cu cream subscription plans from Profusions: 0.5% at $199 per month, 2% at $249 per month, and 4% at $299 per month. Each strength is supplied in 30 mL. Its product page describes these as subscriptions that may be canceled.
Profusions also advertises lower monthly-equivalent prices on three-month plans: $133 for 0.5%, $166 for 2%, and $200 for 4%. Those require the longer plan; they are not the monthly plans shown above. Provider review and shipping are included. Final cost can depend on clinical review.
Profusions identifies 503A and 503B pharmacy sourcing on its website. This is a provider-level sourcing statement; the cream page does not identify its dispensing pharmacy. The table does not imply FDA approval.
Other researched options: Levers lists a 3% cream at $167 for 30 g, with no mandatory automatic subscription. It is not included in the subscription column.
signal-rx: $115 for 30 mL of 0.5% cream per order. There’s no visit fee. You’re only charged if a provider approves. These are selected listed offers, not a market average or an equal-quantity savings calculation. Prices checked September 17, 2026. Other-provider packaging is illustrative.
No subscriptions. Order as you need.
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Quick, simple, easy
I wanted to get a face cream. I was looking for this type of cream for a while and this website has the best price. I ordered and it was a very easy a quick process. I filled out the questionnaire, received a quick approval, paid for the product and received it within 2 days. Great service. Thank you
Great job. Quick response.
I noticed I put the wrong number in my address after I already sent everything. Thought for sure that was going to be a mess. Sent them a message and they fixed it before it shipped. They even let me know it was corrected so I wasn’t sitting there worrying about it.
No surprises at checkout
I liked that I didn’t have to hunt around for the real price. Everything was shown upfront and what I saw was what I paid.
A Truly Positive and Professional Personal Experience
Based on my personal experience, Signal-Rx provides exceptional service and outstanding products, backed by a team that is remarkably knowledgeable, professional, and polite.
How it works
Three steps.
No ongoing commitment.
Get prequalified in 2 minutes.
Share your health history, skin goals and current skin-care routine online.
Check out. Pay nothing yet.
Your card is only held, not charged. Then verify your ID and answer a few last health questions.
Approved? It ships.
A licensed provider reviews every request within 24 hours. You’re only charged if approved: your 30 mL cream, in the strength your provider confirms, shipping included. A one-time purchase, never a subscription.
One cream. Your skin goals.
GHK-Cu is a copper-binding peptide used in topical skin care. This prescription cream brings it into a routine focused on texture, firmness, fine lines and radiance. Your provider selects the strength. Results and timing vary.
Smoother-looking texture
A focused skin-care goal: a smoother, more even-looking surface.
Firmness & fine lines
Build your routine around firmer-looking skin and softer-looking fine lines.
More radiance
Keep a brighter, more radiant-looking complexion in focus.
Before you start
Questions,
answered.
What happens after I start?
Answer a few quick health questions online. It takes about 2 minutes and it’s free. Then check out once: your card is only held, not charged. Verify your ID and answer a few last health questions, and a licensed provider reviews your request within 24 hours and confirms your strength. If approved, you’re charged and your GHK-Cu Cream ships. If nothing is approved, you cancel, or the hold expires, the hold is released, so there is nothing to refund. A prescription is not guaranteed.
What does the $115 cover?
$115 covers one 30 mL bottle of your selected GHK-Cu Cream strength, with standard shipping included. There’s no visit fee. You’re only charged if a provider approves.
Is this a subscription?
No. There are no subscriptions, automatic charges or automatic refills. You choose when to request another order. Each order still requires provider approval.
Which strength should I choose?
Select 0.5%, 2% or 4% for review. Every option contains 30 mL. Your provider considers your skin, sensitivity and current routine before prescribing. Higher strength is not automatically better.
How do I use it with my skin-care routine?
Follow your pharmacy label for the amount, frequency and skin area. Include your current skin-care products, allergies, sensitivity and recent procedures in the intake. Follow your provider’s instructions before combining it with strong actives.
How is it delivered?
Shipping is included. It ships within 1 to 2 business days of approval, and most orders arrive within 2 business days after they ship. Follow the pharmacy label for storage and handling.
Prescription
GHK-Cu Cream
0.5% cream · 30 mL Change strength
No subscriptions. Order as you need.
You pay once, and only if a provider approves.
See important safety information
GHK-Cu Cream is a compounded prescription topical available in 0.5%, 2%, and 4% strengths. Use only the provider-selected strength and follow the exact amount, frequency, and treatment area on the pharmacy label.
Before using the cream
Tell the provider about sensitive skin, eczema, rosacea, copper sensitivity or other allergies, open or irritated areas, recent cosmetic procedures, pregnancy or breastfeeding, and every prescription or nonprescription topical you use.
Topical use only
Apply only to provider-directed skin areas. Avoid unintended contact with the eyes, mouth, and other mucous membranes. Do not apply to broken, infected, or severely irritated skin unless the prescriber specifically directs it. Wash your hands after use.
Other active skincare
Retinoids, exfoliating acids, vitamin C, medicated topicals, and recently treated skin may affect tolerability. Do not add new strong actives, change the prescribed strength, or increase use because results feel slow without provider guidance.
Possible reactions
Possible reactions can include redness, itching, burning, dryness, peeling, tenderness, or rash. Stop using the cream and contact the provider if irritation is persistent, worsening, severe, or difficult to tolerate.
When to seek urgent care
Seek urgent or emergency care for facial swelling, trouble breathing, severe hives, or another severe or rapidly worsening allergic reaction.
Storage and disposal
Store the container exactly as the pharmacy label directs. Keep it away from children and pets, do not share prescription medication, and ask the pharmacy how to dispose of medication you will not use.
About compounded medication
GHK-Cu Cream is compounded for an individual patient pursuant to a prescription. Compounded drugs are not FDA-approved. FDA does not review compounded drugs for safety, effectiveness, or quality before they are marketed.