the USA
subscription
Prescription
Microdosing Tirzepatide
2 months of doses in one vial
A lower-dose approach to GLP-1 care.
One-time purchase. Not a subscription.
2,000+ patients served
You’re charged only if a provider approves. If you’re not approved, the hold is released and you pay nothing. Compounded tirzepatide is not FDA-approved. Prescription required. Pictures are illustrations. signal-rx is not a pharmacy and does not make the medication.
- Cold shipping included
- Licensed U.S. 503A pharmacy
- Syringes included
2 months of doses in one vial.
$260. Not a subscription.
| Order feature |
signal-rx:
One-time package
|
Subscription plans
|
|---|---|---|
| Subscription required | No | Yes |
| Renews or refills on its own | No | Yes |
| Charged only if a provider approves | Yes | Varies |
| Syringes included | Yes | Varies |
“Subscription plans” means recurring plans in general, not any one company. “Varies” means it depends on the plan.
Comparison details
This table compares how a signal-rx one-time package is sold with how recurring subscription plans are sold. It does not compare medications, strengths, doses, results or prices. A subscription plan bills again each period until it is cancelled. Whether a plan charges before a provider decides, and whether it includes syringes, differs from plan to plan, so check the terms of any plan you consider. Reviewed October 12, 2026.
You pay once, and only if a provider approves.
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How it works
Three steps.
No ongoing commitment.
Get prequalified in 2 minutes.
Answer a few quick questions online, then check out. Your card is only held, not charged.
Get your provider review.
Then verify your ID and answer a few last health questions. A licensed U.S. provider reviews your request within 24 hours. If prescribed, your provider sets the dose.
If prescribed, your order is filled.
2 months of doses in one vial. A 2-month supply for $260, syringes included. Nothing renews or refills on its own.
What is microdosing tirzepatide?
Tirzepatide acts on two receptors in your body, GIP and GLP-1. Together they help regulate appetite and blood sugar. Microdosing is a lower-dose approach to GLP-1 care.
Two receptors
Acts on both GIP and GLP-1.
Appetite regulation
Acts on the areas of your brain that regulate appetite.
Blood sugar regulation
Supports insulin release when your blood sugar is high.
How tirzepatide acts is described from FDA labeling for brand-name tirzepatide medicines at their labeled doses. Microdosing is not a dosing regimen approved by the FDA, and its benefits are not established. Compounded tirzepatide is not FDA-approved. Prescription required. Tirzepatide medicines carry an FDA boxed warning about thyroid C-cell tumors. See important safety information.
Before you start
Microdosing tirzepatide FAQs
What happens after I start?
A licensed U.S. provider reviews your request within 24 hours. If prescribed, you’re charged and a licensed U.S. 503A pharmacy fills your order. If not, you pay nothing.
What does the $260 cover?
$260 covers a 2-month supply of compounded tirzepatide, with syringes included. If prescribed, your provider sets the amount and schedule. Shipping included.
Is this a subscription?
No. It’s a one-time purchase. Nothing renews or refills on its own.
What if I’m not approved?
You pay nothing. The hold on your card is released. A prescription isn’t guaranteed.
What does “compounded” mean?
A pharmacy prepares it for one patient, by prescription. Compounded tirzepatide is not FDA-approved. FDA does not review compounded drugs for safety, effectiveness, or quality before they are marketed. It is not a brand-name medicine.
What comes with my order?
If prescribed: a 2-month supply of compounded tirzepatide, with syringes included. A licensed U.S. 503A pharmacy fills it. Your prescription label and your provider’s instructions tell you how to use it.
When will my order arrive?
If a provider approves, your vial ships within 1 to 2 business days, cold, with tracking. It ships to your home. No work addresses or PO boxes.
See important safety information
Read this before you request treatment. It summarizes warnings in FDA labeling for brand-name tirzepatide medicines. It is not a complete list. Compounded tirzepatide is not FDA-approved. A licensed provider decides whether treatment is appropriate for you. If treatment is prescribed, the prescription label and the provider’s instructions control how the medication is used.
Boxed warning: risk of thyroid C-cell tumors
In studies in rats, tirzepatide caused thyroid C-cell tumors. It is not known whether it causes thyroid C-cell tumors, including medullary thyroid carcinoma (MTC), in people. Tell your provider about a lump or swelling in your neck, trouble swallowing, shortness of breath, or hoarseness that does not go away.
Who should not take it
Do not take tirzepatide if you or a family member has ever had medullary thyroid carcinoma (MTC), if you have Multiple Endocrine Neoplasia syndrome type 2 (MEN 2), or if you have had a serious allergic reaction to tirzepatide or any of its ingredients. FDA labeling also says it is not recommended together with another tirzepatide product or any GLP-1 medicine.
Pancreas and gallbladder
Inflammation of the pancreas (pancreatitis), including severe and fatal cases, has been reported with this class of medicines. Stop using it and get medical help for severe stomach-area pain that does not go away, with or without vomiting, which may spread to your back. Gallstones and gallbladder inflammation have also been reported.
Stomach, bowel and kidneys
Stomach and bowel reactions such as nausea, vomiting and diarrhea can be severe. Tirzepatide is not recommended for people with severe gastroparesis (very slow stomach emptying). Vomiting or diarrhea can cause dehydration, which has led to sudden kidney injury, in some cases needing dialysis. Tell your provider about vomiting or diarrhea that does not stop.
Low blood sugar and diabetic eye disease
The risk of low blood sugar is higher if you also take insulin or a sulfonylurea. Low blood sugar has also been reported in people without diabetes. In people with diabetes, a fast improvement in blood sugar can temporarily worsen diabetic eye disease (retinopathy). Tell your provider if you have diabetes or take diabetes medicines.
Other medicines
Tell your provider about all the medicines you take. This medicine slows stomach emptying, which can change how pills are absorbed.
Allergic reactions and procedures
Serious allergic reactions have been reported. Stop using it and get emergency care for swelling of the face, lips, tongue or throat, or trouble breathing. Tell your provider if you have had a serious allergic reaction to another GLP-1 medicine. Tirzepatide slows stomach emptying. Rarely, stomach contents have entered the lungs during procedures with anesthesia or deep sedation, so tell your provider before any surgery or procedure.
Pregnancy and breastfeeding
Weight loss offers no benefit during pregnancy and may harm an unborn baby; tirzepatide should be stopped when pregnancy is recognized. Tirzepatide can make birth control pills less effective. FDA labeling advises using a non-oral method, or adding a barrier method, for 4 weeks after starting and for 4 weeks after each dose increase. Tell your provider if you are pregnant, planning a pregnancy or breastfeeding.
When to seek emergency care
Seek emergency medical care right away for trouble breathing, swelling of the face, lips, tongue or throat, fainting, chest pain, severe stomach-area pain that does not go away, or vomiting that will not stop. This service is not for emergencies.
Measuring and handling a compounded medication
FDA has received reports of dosing errors with compounded injectable GLP-1 medicines, including people measuring the wrong amount; some needed hospital care. Follow your prescription label exactly, and ask your provider or pharmacy before your first dose if you are not sure how to measure it. Use a new sterile needle and syringe every time and never share them. Follow the pharmacy label for storage. Dispose of used needles and syringes in a sharps container. Keep everything away from children.
Complete compounded-medication disclosure
Compounded Tirzepatide is compounded for an individual patient by prescription. Compounded drugs are not FDA-approved, and FDA does not review them for safety, effectiveness, or quality before marketing. FDA labeling for brand-name tirzepatide medicines does not describe microdosing, and the benefits of microdosing are not established. The provider determines whether treatment is appropriate.