B12 doesn’t need to be complicated.

Compare signal-rx orders with recurring B12 subscription plans.
Order feature signal-rx: One-time package Subscription plans
Total B1250 mg5×10 mg*
Subscription requiredNoYes
Automatic billingNoYes
10 mL B12$65per order$90–179*per month
Compounding pharmacyYesVaries
Comparison details

5× the total B12 in AgelessRx’s listed 10 mg vial. Selected monthly offers shown; quantities, prices and terms vary.

Quantity reference: AgelessRx lists 10 mL at 1,000 mcg/mL (10 mg total); signal-rx supplies 10 mL at 5 mg/mL (50 mg total). This quantity comparison applies to the listed AgelessRx vial, not every provider or treatment outcome. Selected standard monthly price references, checked September 15, 2026: AgelessRx $90, Idgie Health $129, and Layla $179 after its introductory offer. These are selected offers, not a market average or equivalent-dose comparison. AgelessRx’s main product page also advertises starting $65/month on a three-month plan and offers one-time purchases. Subscription and automatic-billing rows refer only to selected recurring plans. Included services and formulations vary. signal-rx has no visit fee, and you’re only charged if a provider approves. Pharmacy information varies by provider and dispensing pharmacy; Idgie Health specifically lists a U.S. 503A pharmacy.

You pay once, and only if a provider approves.

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Move forward with confidence.

2,000+ patients served

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Quick, simple, easy

I wanted to get a face cream. I was looking for this type of cream for a while and this website has the best price. I ordered and it was a very easy a quick process. I filled out the questionnaire, received a quick approval, paid for the product and received it within 2 days. Great service. Thank you

Jackie
Verified

Great job. Quick response.

I noticed I put the wrong number in my address after I already sent everything. Thought for sure that was going to be a mess. Sent them a message and they fixed it before it shipped. They even let me know it was corrected so I wasn’t sitting there worrying about it.

Jason
Verified

No surprises at checkout

I liked that I didn’t have to hunt around for the real price. Everything was shown upfront and what I saw was what I paid.

Bethany
Verified

A Truly Positive and Professional Personal Experience

Based on my personal experience, Signal-Rx provides exceptional service and outstanding products, backed by a team that is remarkably knowledgeable, professional, and polite.

Gary
Verified

How it works

Three steps.
No ongoing commitment.

  1. Complete your intake.

    Complete your online intake with your health information.

  2. Get your provider review.

    A licensed provider reviews your information and determines whether to prescribe.

  3. Approved? It ships.

    A licensed provider reviews every request within 24 hours. You’re only charged if approved: 10 mL of B12 for $65, shipping included. A one-time purchase, never a subscription.

What is B12?

B12 is an essential vitamin. It supports your nerves, red blood cells, and normal metabolism.

  • Nerve support

    Helps keep your nervous system working normally.

  • Healthy red blood cells

    Supports the formation of red blood cells.

  • Metabolism and DNA

    Helps your body process nutrients and make DNA.

Before you start

B12 injectable FAQs

What happens after I start?

Answer a few quick health questions online. It takes about 2 minutes and it’s free. Then check out once: your card is only held, not charged. Verify your ID and answer a few last health questions, and a licensed provider reviews your request within 24 hours. If approved, you’re charged and your B12 ships. If nothing is approved, you cancel, or the hold expires, the hold is released, so there is nothing to refund. A prescription is not guaranteed.

What does the $65 cover?

$65 covers 10 mL of B12 (50 mg total), with syringes, needles, alcohol wipes and shipping included. There’s no visit fee. You’re only charged if a provider approves.

Is this a subscription?

No. It’s a one-time purchase. No membership, and nothing renews or refills on its own.

What if I’m not approved?

You pay nothing. The hold on your card is released, so there is nothing to refund. A prescription is not guaranteed.

What comes with my order?

Your B12 is cold shipped with syringes, needles, and alcohol wipes included.

When will my order arrive?

Your order ships within 1 to 2 business days of approval. Most orders arrive within 2 business days after they ship.

Signal-RX B12 injectable vial, front view

Prescription

B12 Injectable

One-time purchase.

$6510 mL

No subscriptions or automatic refills.

Signal-RX B12 injectable vial, front view

See important safety information

Use only as prescribed. The provider and label control amount, administration, schedule, storage, handling, and disposal.

Before treatment

Disclose your health history, allergies, medications, supplements, pregnancy, breastfeeding, digestive history, and prior B12 evaluation.

Injection-site reactions

Redness, pain, itching, or swelling can occur at an injection site. Contact the provider if it persists, worsens, or concerns you.

Sterile handling and disposal

Use a new sterile needle and syringe each time. Never share the medication or injection supplies. Dispose of used items in an appropriate sharps container; one is not supplied.

When to seek emergency care

Seek urgent care for trouble breathing, facial or throat swelling, fainting, severe allergy, or rapidly worsening symptoms.

Complete compounded-medication disclosure

B12 Injectable is compounded by prescription. Compounded drugs are not FDA-approved or reviewed by FDA for safety, effectiveness, or quality before marketing.